The Zebrafishfade outMutant: A Novel Genetic Model for Hermansky–Pudlak Syndrome

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The Zebrafish fade out mutant: a novel genetic model for Hermansky-Pudlak syndrome.

PURPOSE To characterize retinal morphology and visual system function in the zebrafish mutant fade out (fad) and to establish the mutant as a lower vertebrate model for Hermansky-Pudlak syndrome (HPS). METHODS Retinal morphology of fad larvae was examined between 3 and 9 days postfertilization (dpf) by standard histology, transmission electron microscopy, and immunohistochemistry examination....

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ژورنال

عنوان ژورنال: Investigative Opthalmology & Visual Science

سال: 2006

ISSN: 1552-5783

DOI: 10.1167/iovs.05-1596